Version 5.4
Bos taurus Protein: SURF6
Summary
InnateDB Protein IDBP-692890.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SURF6
Protein Name Surfeit locus protein 6
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000015353
InnateDB Gene IDBG-640603 (SURF6)
Protein Structure
UniProt Annotation
Function Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleoplasm {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Granular component of the nucleolus. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0042254 ribosome biogenesis
Cellular Component
GO:0001652 granular component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR029190 Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain
PFAM PF04935
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0VCY3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 511610
UniGene Bt.15527
RefSeq NP_001068997
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC119935
GenPept AAI19936

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca