InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.102259

Summary

InnateDB Protein

IDBP-692909.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.102259

Protein Name

integrin alpha-6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022960

InnateDB Gene

IDBG-640606 (BT.102259)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005178	integrin binding
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007160	cell-matrix adhesion
GO:0007229	integrin-mediated signaling pathway
GO:0022409	positive regulation of cell-cell adhesion
GO:0031589	cell-substrate adhesion
GO:0031668	cellular response to extracellular stimulus
GO:0033627	cell adhesion mediated by integrin
GO:0042327	positive regulation of phosphorylation
GO:0042475	odontogenesis of dentin-containing tooth
GO:0043065	positive regulation of apoptotic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046847	filopodium assembly
GO:0050873	brown fat cell differentiation
GO:0050900	leukocyte migration
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0005604	basement membrane
GO:0005886	plasma membrane
GO:0008305	integrin complex
GO:0009897	external side of plasma membrane
GO:0009925	basal plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0030056	hemidesmosome
GO:0045178	basal part of cell

Protein Structure and Domains

PDB ID

InterPro

IPR000413 Integrin alpha chain
IPR013517 FG-GAP repeat
IPR013519 Integrin alpha beta-propellor
IPR013649 Integrin alpha-2
IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved site

PFAM

PF01839
PF14312
PF08441
PF00357

PRINTS

PR01185

PIRSF

SMART

SM00191

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt