InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PTK6

Summary

InnateDB Protein

IDBP-692913.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTK6

Protein Name

PTK6 protein tyrosine kinase 6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053595

InnateDB Gene

IDBG-640628 (PTK6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0042802	identical protein binding

Biological Process

GO:0006468	protein phosphorylation
GO:0010976	positive regulation of neuron projection development
GO:0016310	phosphorylation
GO:0016477	cell migration
GO:0042503	tyrosine phosphorylation of Stat3 protein
GO:0042506	tyrosine phosphorylation of Stat5 protein
GO:0045926	negative regulation of growth
GO:0046777	protein autophosphorylation
GO:0060575	intestinal epithelial cell differentiation
GO:0061099	negative regulation of protein tyrosine kinase activity
GO:0071300	cellular response to retinoic acid

Cellular Component

GO:0001726	ruffle
GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR000980 SH2 domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452 SH3 domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR011511 Variant SH3 domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM