Version 5.4
Bos taurus Protein: DLX1
Summary
InnateDB Protein IDBP-692916.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DLX1
Protein Name distal-less homeobox 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000020246
InnateDB Gene IDBG-640636 (DLX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0009954 proximal/distal pattern formation
GO:0021544 subpallium development
GO:0021766 hippocampus development
GO:0021879 forebrain neuron differentiation
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
GO:0021892 cerebral cortex GABAergic interneuron differentiation
GO:0021893 cerebral cortex GABAergic interneuron fate commitment
GO:0030154 cell differentiation
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043524 negative regulation of neuron apoptotic process
GO:0045746 negative regulation of Notch signaling pathway
GO:0048706 embryonic skeletal system development
GO:0048715 negative regulation of oligodendrocyte differentiation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000047 Helix-turn-helix motif
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00031
PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6H733
UniProt Splice Variant
Entrez Gene 521806
UniGene Bt.87150
RefSeq NP_001092487
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC146096 DAAA02004227
GenPept AAI46097

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca