InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DEM1

Summary

InnateDB Protein

IDBP-693009.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DEM1

Protein Name

defects in morphology protein 1 homolog

Synonyms

C1orf176; DEM1; Exo V;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000690

InnateDB Gene

IDBG-640723 (DEM1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0004518	nuclease activity
GO:0004527	exonuclease activity
GO:0016787	hydrolase activity
GO:0045145	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

Biological Process

GO:0000738	DNA catabolic process, exonucleolytic
GO:0006281	DNA repair
GO:0006974	cellular response to DNA damage stimulus
GO:0036297	interstrand cross-link repair
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR019190 Exonuclease V

PFAM

PF09810

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A2VDX7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

538883

UniGene

Bt.6374

RefSeq

NP_001075077

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC133457 DAAA02009128

GenPept

AAI33458