InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: AZGP1

Summary

InnateDB Protein

IDBP-693030.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AZGP1

Protein Name

Zinc-alpha-2-glycoprotein

Synonyms

ZAG;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000037042

InnateDB Gene

IDBG-640744 (AZGP1)

Protein Structure

UniProt Annotation

Function

Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0005515	protein binding
GO:0042605	peptide antigen binding

Biological Process

GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
GO:0001895	retina homeostasis
GO:0001916	positive regulation of T cell mediated cytotoxicity
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0006955	immune response
GO:0019882	antigen processing and presentation

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0016020	membrane
GO:0042612	MHC class I protein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein
IPR027648 MHC class I alpha chain

PFAM

PF00129
PF07654

PRINTS

PR01638

PIRSF

SMART

SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3ZCH5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

508800

UniGene

RefSeq

NP_001029503

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102237

GenPept

AAI02238