Version 5.4
Bos taurus Protein: BT.12647
Summary
InnateDB Protein IDBP-693111.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.12647
Protein Name mediator of RNA polymerase II transcription subunit 25
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000040773
InnateDB Gene IDBG-640804 (BT.12647)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0042974 retinoic acid receptor binding
GO:0046965 retinoid X receptor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0035563 positive regulation of chromatin binding
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048147 negative regulation of fibroblast proliferation
GO:0071158 positive regulation of cell cycle arrest
GO:2001178 positive regulation of mediator complex assembly
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002035 von Willebrand factor, type A
IPR021394 Mediator complex, subunit Med25, PTOV activation and synapsin 2
IPR021397 Mediator complex, subunit Med25, synapsin 1
IPR021419 Mediator complex, subunit Med25, von Willebrand factor type A
PFAM PF00092
PF11232
PF11235
PF11265
PRINTS
PIRSF
SMART SM00327
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N3D4
UniProt Splice Variant
Entrez Gene 533865
UniGene
RefSeq NP_001075914
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047485 DAAA02047486
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca