Version 5.4
Bos taurus Protein: PTOV1
Summary
InnateDB Protein IDBP-693125.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTOV1
Protein Name Prostate tumor-overexpressed gene 1 protein homolog
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000026147
InnateDB Gene IDBG-640817 (PTOV1)
Protein Structure
UniProt Annotation
Function May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR021394 Mediator complex, subunit Med25, PTOV activation and synapsin 2
PFAM PF11232
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A4IFC9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 617775
UniGene Bt.17891
RefSeq NP_001077249
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134519
GenPept AAI34520

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca