Version 5.4
Bos taurus Protein: GATA5
Summary
InnateDB Protein IDBP-693137.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GATA5
Protein Name Transcription factor GATA-5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027184
InnateDB Gene IDBG-640838 (GATA5)
Protein Structure
UniProt Annotation
Function Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001158 enhancer sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060575 intestinal epithelial cell differentiation
GO:0071773 cellular response to BMP stimulus
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000679 Zinc finger, GATA-type
IPR008013 GATA-type transcription activator, N-terminal
IPR016375 Transcription factor GATA-4/5/6
PFAM PF00320
PF05349
PRINTS PR00619
PIRSF PIRSF003028
SMART SM00401
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SZJ5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 504784
UniGene Bt.61958
RefSeq NP_001029393
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102821
GenPept AAI02822

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca