Bos taurus Protein: G6PC3
Summary
InnateDB Protein IDBP-693143.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol G6PC3
Protein Name Glucose-6-phosphatase 3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021621
InnateDB Gene IDBG-640843 (G6PC3)
Protein Structure
UniProt Annotation
Function Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004346 glucose-6-phosphatase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006094 gluconeogenesis
GO:0015760 glucose-6-phosphate transport
GO:0016311 dephosphorylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
IPR016275 Glucose-6-phosphatase
PFAM PF01569
PRINTS
PIRSF PIRSF000905
SMART SM00014
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q148G2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 369023
UniGene Bt.23154
RefSeq NP_899208
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY279358 BC118357
GenPept AAI18358 AAP40635