InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GFPT2

Summary

InnateDB Protein

IDBP-693193.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GFPT2

Protein Name

Glucosamine--fructose-6-phosphate aminotransferase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000002867

InnateDB Gene

IDBG-640889 (GFPT2)

Protein Structure

UniProt Annotation

Function

Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0008483	transaminase activity
GO:0016740	transferase activity
GO:0030246	carbohydrate binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006048	UDP-N-acetylglucosamine biosynthetic process
GO:0006541	glutamine metabolic process
GO:0008152	metabolic process
GO:0016051	carbohydrate biosynthetic process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000583 Class II glutamine amidotransferase domain
IPR001347 Sugar isomerase (SIS)
IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising
IPR029055 Nucleophile aminohydrolases, N-terminal

PFAM

PF00310
PF13537
PF01380
PF13580

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q08DQ2

PhosphoSite