InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PHOSPHO2

Summary

InnateDB Protein

IDBP-693205.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PHOSPHO2

Protein Name

Pyridoxal phosphate phosphatase PHOSPHO2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001446

InnateDB Gene

IDBG-640899 (PHOSPHO2)

Protein Structure

UniProt Annotation

Function

Phosphatase that has high activity toward pyridoxal 5'- phosphate (PLP). Also active at much lower level toward pyrophosphate, phosphoethanolamine (PEA), phosphocholine (PCho), phospho-l-tyrosine, fructose-6-phosphate, p-nitrophenyl phosphate, and h-glycerophosphate (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity
GO:0033883	pyridoxal phosphatase activity
GO:0046872	metal ion binding

Biological Process

GO:0008152	metabolic process
GO:0016311	dephosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like
IPR006384 Pyridoxal phosphate phosphatase-related
IPR016965 Phosphatase PHOSPHO-type
IPR023214 HAD-like domain

PFAM

PF06888
PF00702
PF08282
PF13419

PRINTS

PIRSF

PIRSF031051

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2KI06