InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.105440

Summary

InnateDB Protein

IDBP-693238.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.105440

Protein Name

sequestosome-1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020709

InnateDB Gene

IDBG-640935 (BT.105440)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 174 interaction(s) predicted by orthology.

Predicted by orthology
Total	174 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005080	protein kinase C binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0019901	protein kinase binding
GO:0042169	SH2 domain binding
GO:0042802	identical protein binding
GO:0043130	ubiquitin binding
GO:0070530	K63-linked polyubiquitin binding

Biological Process

GO:0006914	autophagy
GO:0016239	positive regulation of macroautophagy
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling

Cellular Component

GO:0000407	pre-autophagosomal structure
GO:0000932	cytoplasmic mRNA processing body
GO:0005737	cytoplasm
GO:0005776	autophagic vacuole
GO:0016234	inclusion body
GO:0016235	aggresome
GO:0016605	PML body
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000270 Phox/Bem1p
IPR000433 Zinc finger, ZZ-type
IPR009060 UBA-like
IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote

PFAM

PF00564
PF00569

PRINTS

PIRSF

SMART

SM00666
SM00291
SM00165

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite