InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ABCB11

Summary

InnateDB Protein

IDBP-693333.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCB11

Protein Name

ATP-binding cassette, sub-family B (MDR/TAP), member 11

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000043977

InnateDB Gene

IDBG-641016 (ABCB11)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005524	ATP binding
GO:0015126	canalicular bile acid transmembrane transporter activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0042626	ATPase activity, coupled to transmembrane movement of substances

Biological Process

GO:0006200	ATP catabolic process
GO:0006810	transport
GO:0008152	metabolic process
GO:0015722	canalicular bile acid transport
GO:0055085	transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045177	apical part of cell
GO:0046581	intercellular canaliculus
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001140 ABC transporter, transmembrane domain
IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR011527 ABC transporter type 1, transmembrane domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00664
PF13748
PF00005

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite