Version 5.4
Bos taurus Protein: POLD1
Summary
InnateDB Protein IDBP-693349.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLD1
Protein Name polymerase (DNA directed), delta 1, catalytic subunit 125kDa
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000014714
InnateDB Gene IDBG-641027 (POLD1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Predicted by orthology
Total 46 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0016740 transferase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0000731 DNA synthesis involved in DNA repair
GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0006287 base-excision repair, gap-filling
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0045004 DNA replication proofreading
GO:0055089 fatty acid homeostasis
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0000109 nucleotide-excision repair complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016235 aggresome
Protein Structure and Domains
PDB ID
InterPro IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain
IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain
IPR006172 DNA-directed DNA polymerase, family B
IPR012337 Ribonuclease H-like domain
PFAM PF03104
PF00136
PRINTS PR00106
PIRSF
SMART SM00486
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BNZ6
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:9175
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047499 DAAA02047500
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca