InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: INPP5B

Summary

InnateDB Protein

IDBP-693424.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

INPP5B

Protein Name

inositol polyphosphate-5-phosphatase, 75kDa

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000033176

InnateDB Gene

IDBG-641057 (INPP5B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005515	protein binding
GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity

Biological Process

GO:0001701	in utero embryonic development
GO:0007165	signal transduction
GO:0007283	spermatogenesis
GO:0030317	sperm motility
GO:0046856	phosphatidylinositol dephosphorylation
GO:0070613	regulation of protein processing

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0015630	microtubule cytoskeleton
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000198 Rho GTPase-activating protein domain
IPR000300 Inositol polyphosphate-related phosphatase
IPR005135 Endonuclease/exonuclease/phosphatase
IPR008936 Rho GTPase activation protein

PFAM

PF00620
PF03372
PF14529

PRINTS

PIRSF

SMART

SM00324
SM00128

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite