InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: STK40

Summary

InnateDB Protein

IDBP-693632.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STK40

Protein Name

Serine/threonine-protein kinase 40

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000021243

InnateDB Gene

IDBG-641287 (STK40)

Protein Structure

UniProt Annotation

Function

May be a negative regulator of NF-kappa-B and p53- mediated gene transcription. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0003016	respiratory system process
GO:0005977	glycogen metabolic process
GO:0006468	protein phosphorylation
GO:0010468	regulation of gene expression
GO:0016310	phosphorylation
GO:0030324	lung development
GO:0035264	multicellular organism growth
GO:0043066	negative regulation of apoptotic process
GO:0043408	regulation of MAPK cascade
GO:0048286	lung alveolus development
GO:0060425	lung morphogenesis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q17QV9

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

515723

UniGene

Bt.31357

RefSeq

NP_001069195

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC118150

GenPept

AAI18151