Version 5.4
| Bos taurus Protein: NSFL1C | |||||||||||||||
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| Summary | |||||||||||||||
| InnateDB Protein | IDBP-693743.2 | ||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
| Gene Symbol | NSFL1C | ||||||||||||||
| Protein Name | NSFL1 cofactor p47 | ||||||||||||||
| Synonyms | |||||||||||||||
| Species | Bos taurus | ||||||||||||||
| Ensembl Protein | ENSBTAP00000008580 | ||||||||||||||
| InnateDB Gene | IDBG-641382 (NSFL1C) | ||||||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||||||
| Function | Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER) (By similarity). {ECO:0000250}. | ||||||||||||||
| Subcellular Localization | Nucleus {ECO:0000250}. Golgi apparatus, Golgi stack {ECO:0000250}. Chromosome {ECO:0000250}. Note=Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks (By similarity). {ECO:0000250}. | ||||||||||||||
| Disease Associations | |||||||||||||||
| Tissue Specificity | |||||||||||||||
| Comments | |||||||||||||||
| Interactions | |||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||||||
| PDB ID | |||||||||||||||
| InterPro |
IPR001012
UBX domain IPR009060 UBA-like IPR012989 SEP domain IPR029071 Ubiquitin-related domain |
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| PFAM |
PF00789
PF08059 |
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| PRINTS | |||||||||||||||
| PIRSF | |||||||||||||||
| SMART |
SM00166
SM00553 |
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| TIGRFAMs | |||||||||||||||
| Post-translational Modifications | |||||||||||||||
| Modification | |||||||||||||||
| Cross-References | |||||||||||||||
| SwissProt | Q3SZC4 | ||||||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||||||
| TrEMBL | |||||||||||||||
| UniProt Splice Variant | |||||||||||||||
| Entrez Gene | 526612 | ||||||||||||||
| UniGene | Bt.53665 | ||||||||||||||
| RefSeq | NP_001029729 | ||||||||||||||
| HUGO | |||||||||||||||
| OMIM | |||||||||||||||
| CCDS | |||||||||||||||
| HPRD | |||||||||||||||
| IMGT | |||||||||||||||
| EMBL | BC102956 | ||||||||||||||
| GenPept | AAI02957 | ||||||||||||||