InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC52A3

Summary

InnateDB Protein

IDBP-693814.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC52A3

Protein Name

Riboflavin transporter 2

Synonyms

C13H20orf54; C20orf54; RFT2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005194

InnateDB Gene

IDBG-641450 (SLC52A3)

Protein Structure

UniProt Annotation

Function

Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), and to a lesser extent by amiloride (By similarity). {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0032217	riboflavin transporter activity

Biological Process

GO:0006810	transport
GO:0007605	sensory perception of sound
GO:0032218	riboflavin transport
GO:0034605	cellular response to heat

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR009357 Endogenous retrovirus receptor

PFAM

PF06237

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5E9R1

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

507459

UniGene

Bt.27910

RefSeq

NP_001014864

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102546 BT020859

GenPept

AAI02547 AAX08876