Version 5.4
Bos taurus Protein: GET4
Summary
InnateDB Protein IDBP-693840.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GET4
Protein Name Golgi to ER traffic protein 4 homolog
Synonyms C25H7ORF20;
Species Bos taurus
Ensembl Protein ENSBTAP00000036940
InnateDB Gene IDBG-641469 (GET4)
Protein Structure
UniProt Annotation
Function Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0071818 BAT3 complex
Protein Structure and Domains
PDB ID
InterPro IPR007317 Uncharacterised protein family UPF0363
PFAM PF04190
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0P5I8
PhosphoSite PhosphoSite-
TrEMBL F1MQU5
UniProt Splice Variant
Entrez Gene 618954
UniGene Bt.29993
RefSeq NP_001069993
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC119983 DAAA02058421
GenPept AAI19984

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca