InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PHPT1

Summary

InnateDB Protein

IDBP-693855.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PHPT1

Protein Name

14 kDa phosphohistidine phosphatase

Synonyms

PHP14;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028712

InnateDB Gene

IDBG-641489 (PHPT1)

Protein Structure

UniProt Annotation

Function

Exhibits phosphohistidine phosphatase activity. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0008969	phosphohistidine phosphatase activity
GO:0016787	hydrolase activity
GO:0019855	calcium channel inhibitor activity
GO:0044325	ion channel binding

Biological Process

GO:0006470	protein dephosphorylation
GO:0035971	peptidyl-histidine dephosphorylation
GO:0050860	negative regulation of T cell receptor signaling pathway
GO:0051350	negative regulation of lyase activity
GO:2000147	positive regulation of cell motility
GO:2000249	regulation of actin cytoskeleton reorganization
GO:2000984	negative regulation of ATP citrate synthase activity

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR007702 Janus

PFAM

PF05005

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q32PA4

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

618691

UniGene

Bt.53499

RefSeq

NP_001069984

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC108196

GenPept

AAI08197