Version 5.4
Bos taurus Protein: BAIAP2L2
Summary
InnateDB Protein IDBP-693967.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BAIAP2L2
Protein Name Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000020331
InnateDB Gene IDBG-641575 (BAIAP2L2)
Protein Structure
UniProt Annotation
Function Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}. Note=Localizes to RAB13-positive vesicles and to the plasma membrane at intercellular contacts. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0008093 cytoskeletal adaptor activity
GO:0008289 lipid binding
GO:0017124 SH3 domain binding
Biological Process
GO:0007009 plasma membrane organization
GO:0007165 signal transduction
GO:0032956 regulation of actin cytoskeleton organization
GO:0046847 filopodium assembly
GO:0061024 membrane organization
Cellular Component
GO:0005886 plasma membrane
GO:0012506 vesicle membrane
GO:0016020 membrane
GO:0030054 cell junction
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0044291 cell-cell contact zone
GO:0071439 clathrin complex
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR011511 Variant SH3 domain
IPR013606 IRSp53/MIM homology domain (IMD)
PFAM PF00018
PF14604
PF07653
PF08397
PRINTS PR00452
PIRSF
SMART SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt E1BFE9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 617924
UniGene
RefSeq XP_005207407
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03031682 AAFC03051115
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca