Version 5.4
Bos taurus Protein: UPF1
Summary
InnateDB Protein IDBP-693987.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UPF1
Protein Name UPF1 regulator of nonsense transcripts homolog (yeast)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027868
InnateDB Gene IDBG-641582 (UPF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 93 interaction(s) predicted by orthology.
Predicted by orthology
Total 93 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0004004 ATP-dependent RNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0006200 ATP catabolic process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0009048 dosage compensation by inactivation of X chromosome
GO:0071044 histone mRNA catabolic process
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0035145 exon-exon junction complex
GO:0044530 supraspliceosomal complex
Protein Structure and Domains
PDB ID
InterPro IPR006935 Helicase/UvrB domain
IPR018999 RNA helicase UPF1, UPF2-interacting domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF04851
PF09416
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BEK9
UniProt Splice Variant
Entrez Gene 532933
UniGene
RefSeq XP_002688572
HUGO HGNC:9962
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02019036
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca