InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CRLF1

Summary

InnateDB Protein

IDBP-694031.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CRLF1

Protein Name

cytokine receptor-like factor 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010179

InnateDB Gene

IDBG-641642 (CRLF1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005127	ciliary neurotrophic factor receptor binding
GO:0005515	protein binding
GO:0019955	cytokine binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001657	ureteric bud development
GO:0008284	positive regulation of cell proliferation
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043524	negative regulation of neuron apoptotic process
GO:2000672	negative regulation of motor neuron apoptotic process

Cellular Component

GO:0097058

CRLF-CLCF1 complex

Protein Structure and Domains

PDB ID

InterPro

IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR015152 Growth hormone/erythropoietin receptor, ligand binding
IPR015321 Interleukin-6 receptor alpha, binding

PFAM

PF00041
PF01108
PF09067
PF09240

PRINTS

PIRSF

SMART

SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite