Version 5.4
Bos taurus Protein: TOMM22
Summary
InnateDB Protein IDBP-694053.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOMM22
Protein Name Mitochondrial import receptor subunit TOM22 homolog
Synonyms Tom22;
Species Bos taurus
Ensembl Protein ENSBTAP00000013405
InnateDB Gene IDBG-641672 (TOMM22)
Protein Structure
UniProt Annotation
Function Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.
Subcellular Localization Mitochondrion outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0045040 protein import into mitochondrial outer membrane
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005742 mitochondrial outer membrane translocase complex
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR005683 Mitochondrial outer membrane translocase complex, subunit Tom22
PFAM PF04281
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6QPI6
PhosphoSite PhosphoSite-
TrEMBL E2GEZ1
UniProt Splice Variant
Entrez Gene 510780
UniGene
RefSeq NP_001093805
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149339 HM347496
GenPept AAI49340 ADK26448

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca