InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GJB3

Summary

InnateDB Protein

IDBP-694098.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GJB3

Protein Name

Gap junction beta-3 protein

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016705

InnateDB Gene

IDBG-641711 (GJB3)

Protein Structure

UniProt Annotation

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001890	placenta development
GO:0007154	cell communication

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005921	gap junction
GO:0005922	connexon complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction

Protein Structure and Domains

PDB ID

InterPro

IPR000500 Connexin
IPR002269 Gap junction beta-3 protein (Cx31)
IPR013092 Connexin, N-terminal
IPR019570 Gap junction protein, cysteine-rich domain

PFAM

PF00029
PF10582

PRINTS

PR00206
PR01140

PIRSF

SMART

SM00037
SM01089

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q58D78

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

539935

UniGene

Bt.37383

RefSeq

NP_001098465

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC133376 BT021719

GenPept

AAI33377 AAX46566