InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DYNLRB1

Summary

InnateDB Protein

IDBP-694309.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DYNLRB1

Protein Name

Dynein light chain roadblock-type 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000008068

InnateDB Gene

IDBG-641904 (DYNLRB1)

Protein Structure

UniProt Annotation

Function

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0006810	transport
GO:0008152	metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005856	cytoskeleton
GO:0005868	cytoplasmic dynein complex
GO:0005874	microtubule
GO:0016020	membrane
GO:0030286	dynein complex

Protein Structure and Domains

PDB ID

InterPro

IPR004942 Dynein light chain-related
IPR016561 Dynein light chain, roadblock-type

PFAM

PF03259

PRINTS

PIRSF

PIRSF009998

SMART

SM00960

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3T140

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

513342

UniGene

RefSeq

NP_001029614

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102138

GenPept

AAI02139