Version 5.4
Bos taurus Protein: C29H11orf73
Summary
InnateDB Protein IDBP-694325.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C29H11orf73
Protein Name Uncharacterized protein C11orf73 homolog
Synonyms C11orf73;
Species Bos taurus
Ensembl Protein ENSBTAP00000026632
InnateDB Gene IDBG-641917 (C29H11orf73)
Protein Structure
UniProt Annotation
Function Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008565 protein transporter activity
GO:0030544 Hsp70 protein binding
Biological Process
GO:0006606 protein import into nucleus
GO:0006810 transport
GO:0007030 Golgi organization
GO:0015031 protein transport
GO:0030324 lung development
GO:0034605 cellular response to heat
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030054 cell junction
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008493 Protein of unknown function DUF775
PFAM PF05603
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q56JY0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 504867
UniGene Bt.8351
RefSeq NP_001029398
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY911348 BC103227
GenPept AAI03228 AAW82115

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca