Version 5.4
Bos taurus Protein: SMURF2
Summary
InnateDB Protein IDBP-694332.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMURF2
Protein Name SMAD specific E3 ubiquitin protein ligase 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000026451
InnateDB Gene IDBG-641903 (SMURF2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 120 interaction(s) predicted by orthology.
Predicted by orthology
Total 120 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016874 ligase activity
GO:0042802 identical protein binding
GO:0046332 SMAD binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016567 protein ubiquitination
GO:0030579 ubiquitin-dependent SMAD protein catabolic process
Cellular Component
GO:0000151 ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR000569 HECT
IPR001202 WW domain
PFAM PF00168
PF00632
PF00397
PRINTS PR00360
PIRSF
SMART SM00239
SM00119
SM00456
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N3W8
UniProt Splice Variant
Entrez Gene 540826
UniGene Bt.105456
RefSeq XP_002696169
HUGO HGNC:16809
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049347
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca