Version 5.4
Bos taurus Protein: NCR1
Summary
InnateDB Protein IDBP-694409.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCR1
Protein Name Natural cytotoxicity triggering receptor 1
Synonyms NKP46;
Species Bos taurus
Ensembl Protein ENSBTAP00000053976
InnateDB Gene IDBG-641998 (NCR1)
Protein Structure
UniProt Annotation
Function Cytotoxicity activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Selectively expressed by NK cells. {ECO:0000269PubMed:12672064}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013151 Immunoglobulin
PFAM PF00047
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q863H2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 369024
UniGene Bt.23155
RefSeq NP_899209
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF422181
GenPept AAP33623

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca