Version 5.4
Bos taurus Protein: CENPM
Summary
InnateDB Protein IDBP-694435.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CENPM
Protein Name Centromere protein M
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000013133
InnateDB Gene IDBG-642020 (CENPM)
Protein Structure
UniProt Annotation
Function Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus. Cytoplasm. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Nuclear in non-confluent cells and cytoplasmic in confluent or dividing cells. Localizes in the kinetochore domain of centromeres (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR020987 Centromere protein Cenp-M
PFAM PF11111
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2TBH1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 615953
UniGene
RefSeq NP_001033775
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC110230
GenPept AAI10231

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca