InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FAM109B

Summary

InnateDB Protein

IDBP-694456.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FAM109B

Protein Name

Sesquipedalian-2

Synonyms

IPIP27B; Ses2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000012510

InnateDB Gene

IDBG-642042 (FAM109B)

Protein Structure

UniProt Annotation

Function

Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane (By similarity). {ECO:0000250}.

Subcellular Localization

Early endosome {ECO:0000250}. Recycling endosome {ECO:0000250}. Golgi apparatus, trans-Golgi network {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0001881	receptor recycling
GO:0007032	endosome organization
GO:0042147	retrograde transport, endosome to Golgi

Cellular Component

GO:0005768	endosome
GO:0005769	early endosome
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0030136	clathrin-coated vesicle
GO:0031410	cytoplasmic vesicle
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

InterPro

IPR001849 Pleckstrin homology domain

PFAM

PF00169

PRINTS

PIRSF

SMART

SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q1RMU7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

506148

UniGene

Bt.5202

RefSeq

NP_001039401

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC114700

GenPept

AAI14701