InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLAIN2

Summary

InnateDB Protein

IDBP-694536.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLAIN2

Protein Name

SLAIN motif-containing protein 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000029282

InnateDB Gene

IDBG-642120 (SLAIN2)

Protein Structure

UniProt Annotation

Function

Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007020	microtubule nucleation
GO:0031113	regulation of microtubule polymerization
GO:0031116	positive regulation of microtubule polymerization
GO:0031122	cytoplasmic microtubule organization

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005856	cytoskeleton
GO:0015630	microtubule cytoskeleton
GO:0035371	microtubule plus-end