InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NDUFC2

Summary

InnateDB Protein

IDBP-694570.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDUFC2

Protein Name

NADH dehydrogenase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000024209

InnateDB Gene

IDBG-642144 (NDUFC2)

Protein Structure

UniProt Annotation

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular Localization

Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008137	NADH dehydrogenase (ubiquinone) activity

Biological Process

GO:0006120	mitochondrial electron transport, NADH to ubiquinone
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070469	respiratory chain

Protein Structure and Domains

PDB ID

InterPro

IPR009423 NADH:ubiquinone oxidoreductase, subunit b14.5b

PFAM

PF06374

PRINTS

PIRSF

PIRSF017834

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q02827

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

338046

UniGene

RefSeq

NP_788815

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102739 X68647

GenPept

AAI02740 CAA48607