Version 5.4
Bos taurus Protein: TMEM38A
Summary
InnateDB Protein IDBP-694646.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM38A
Protein Name Trimeric intracellular cation channel type A
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018099
InnateDB Gene IDBG-642213 (TMEM38A)
Protein Structure
UniProt Annotation
Function Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). {ECO:0000250}.
Subcellular Localization Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005261 cation channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0015672 monovalent inorganic cation transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016529 sarcoplasmic reticulum
GO:0031965 nuclear membrane
GO:0033017 sarcoplasmic reticulum membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR007866 TRIC channel
PFAM PF05197
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A4FV75
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 532775
UniGene Bt.1310
RefSeq NP_001076932
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123825
GenPept AAI23826

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca