Version 5.4
Bos taurus Protein: TFPT
Summary
InnateDB Protein IDBP-694675.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFPT
Protein Name TCF3 fusion partner homolog
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000010195
InnateDB Gene IDBG-642238 (TFPT)
Protein Structure
UniProt Annotation
Function Appears to promote apoptosis in a p53/TP53-independent manner. {ECO:0000250}.Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005884 actin filament
GO:0031011 Ino80 complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q17QH7
PhosphoSite PhosphoSite-
TrEMBL B1GVZ1
UniProt Splice Variant
Entrez Gene 506610
UniGene Bt.62346
RefSeq NP_001068742
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AM930541 AM930552 BC118355
GenPept AAI18356 CAP59622 CAP59632

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca