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InnateDB Protein
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IDBP-694692.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ROMO1
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Protein Name
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Reactive oxygen species modulator 1
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Synonyms
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C13H20ORF52;
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000039044
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InnateDB Gene
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IDBG-642254 (ROMO1)
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Protein Structure
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| Function |
Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage (By similarity). {ECO:0000250}.Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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| Biological Process |
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GO:0001302
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replicative cell aging
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GO:0008284
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positive regulation of cell proliferation
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GO:0034614
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cellular response to reactive oxygen species
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GO:0042742
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defense response to bacterium
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GO:2000379
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positive regulation of reactive oxygen species metabolic process
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR018450
Reactive oxygen species modulator 1
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| PFAM |
PF10247
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q3SZV8
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
618530
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| UniGene |
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| RefSeq |
NP_001108000
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| HUGO |
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
BC102685
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| GenPept |
AAI02686
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Version 5.4