InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: INSIG2

Summary

InnateDB Protein

IDBP-694851.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

INSIG2

Protein Name

insulin induced gene 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053974

InnateDB Gene

IDBG-642387 (INSIG2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006641	triglyceride metabolic process
GO:0006695	cholesterol biosynthetic process
GO:0006991	response to sterol depletion
GO:0008203	cholesterol metabolic process
GO:0010894	negative regulation of steroid biosynthetic process
GO:0016126	sterol biosynthetic process
GO:0032933	SREBP signaling pathway
GO:0042472	inner ear morphogenesis
GO:0042474	middle ear morphogenesis
GO:0045717	negative regulation of fatty acid biosynthetic process
GO:0060021	palate development
GO:0060363	cranial suture morphogenesis

Cellular Component

GO:0032937

SREBP-SCAP-Insig complex

Protein Structure and Domains

PDB ID

InterPro

IPR025929 Insulin-induced protein family

PFAM

PF07281

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3MWS1

UniProt Splice Variant

Entrez Gene

534440

UniGene

RefSeq

XP_003581891

HUGO

HGNC:20452

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02005163

GenPept