InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PGLYRP2

Summary

InnateDB Protein

IDBP-694865.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PGLYRP2

Protein Name

peptidoglycan recognition protein 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000044262

InnateDB Gene

IDBG-642412 (PGLYRP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008270	zinc ion binding
GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
GO:0016019	peptidoglycan receptor activity
GO:0042834	peptidoglycan binding

Biological Process

GO:0002221	pattern recognition receptor signaling pathway
GO:0009253	peptidoglycan catabolic process
GO:0016045	detection of bacterium
GO:0032689	negative regulation of interferon-gamma production
GO:0032827	negative regulation of natural killer cell differentiation involved in immune response
GO:0044117	growth of symbiont in host
GO:0050727	regulation of inflammatory response
GO:0050830	defense response to Gram-positive bacterium

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002502 N-acetylmuramoyl-L-alanine amidase domain
IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria

PFAM

PF01510

PRINTS

PIRSF

SMART

SM00644
SM00701

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1BH94

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

HGNC:30013

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02019132

GenPept