Version 5.4
Bos taurus Protein: TSG101
Summary
InnateDB Protein IDBP-694872.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSG101
Protein Name tumor susceptibility gene 101 protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018032
InnateDB Gene IDBG-642417 (TSG101)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 128 interaction(s) predicted by orthology.
Predicted by orthology
Total 128 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0042803 protein homodimerization activity
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0001558 regulation of cell growth
GO:0006464 cellular protein modification process
GO:0007050 cell cycle arrest
GO:0008285 negative regulation of cell proliferation
GO:0015031 protein transport
GO:0030154 cell differentiation
GO:0030216 keratinocyte differentiation
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046755 non-lytic virus budding
Cellular Component
GO:0000813 ESCRT I complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008883 Ubiquitin E2 variant, N-terminal
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
IPR017916 Steadiness box
PFAM PF05743
PF09454
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A3KN51
UniProt Splice Variant
Entrez Gene 507659
UniGene Bt.67546
RefSeq NP_001091464
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133615 DAAA02062983
GenPept AAI33616

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca