InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CELSR1

Summary

InnateDB Protein

IDBP-694876.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CELSR1

Protein Name

cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010571

InnateDB Gene

IDBG-642404 (CELSR1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0001736	establishment of planar polarity
GO:0001764	neuron migration
GO:0001843	neural tube closure
GO:0001942	hair follicle development
GO:0007165	signal transduction
GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway
GO:0007266	Rho protein signal transduction
GO:0007626	locomotory behavior
GO:0009952	anterior/posterior pattern specification
GO:0032956	regulation of actin cytoskeleton organization
GO:0042060	wound healing
GO:0042249	establishment of planar polarity of embryonic epithelium
GO:0042472	inner ear morphogenesis
GO:0045176	apical protein localization
GO:0048105	establishment of body hair planar orientation
GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis
GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis
GO:0060490	lateral sprouting involved in lung morphogenesis
GO:0090179	planar cell polarity pathway involved in neural tube closure
GO:0090251	protein localization involved in establishment of planar polarity

Cellular Component

GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000203 GPS motif
IPR000742 Epidermal growth factor-like domain
IPR000832 GPCR, family 2, secretin-like
IPR001791 Laminin G domain
IPR001879 GPCR, family 2, extracellular hormone receptor domain
IPR001881 EGF-like calcium-binding domain
IPR002049 EGF-like, laminin
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR017981 GPCR, family 2-like
IPR022624 Domain of unknown function DUF3497

PFAM