InnateDB Protein
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IDBP-694900.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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DBI
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Protein Name
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Acyl-CoA-binding protein
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Synonyms
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ACBP; EP;
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000012523
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InnateDB Gene
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IDBG-642447 (DBI)
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Protein Structure
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Function |
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. {ECO:0000269PubMed:11491287}.
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Subcellular Localization |
Endoplasmic reticulum {ECO:0000269PubMed:17953517}. Golgi apparatus {ECO:0000269PubMed:17953517}. Note=Golgi localization is dependent on ligand binding.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
11 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000582
Acyl-CoA-binding protein, ACBP
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PFAM |
PF00887
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PRINTS |
PR00689
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P07107
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PhosphoSite |
PhosphoSite-P07107
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
768330
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UniGene |
Bt.46917
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RefSeq |
NP_001106792
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC114181
M15886
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GenPept |
AAA30495
AAI14182
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