Version 5.4
Bos taurus Protein: GHRH
Summary
InnateDB Protein IDBP-695014.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GHRH
Protein Name Somatoliberin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000016891
InnateDB Gene IDBG-642549 (GHRH)
Protein Structure
UniProt Annotation
Function GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005515 protein binding
GO:0016608 growth hormone-releasing hormone activity
GO:0031770 growth hormone-releasing hormone receptor binding
Biological Process
GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0019933 cAMP-mediated signaling
GO:0021984 adenohypophysis development
GO:0030252 growth hormone secretion
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0032094 response to food
GO:0040018 positive regulation of multicellular organism growth
GO:0046887 positive regulation of hormone secretion
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0043195 terminal bouton
Protein Structure and Domains
PDB ID
InterPro IPR000532 Glucagon/GIP/secretin/VIP
PFAM PF00123
PRINTS PR00275
PIRSF
SMART SM00070
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P63292
PhosphoSite PhosphoSite-
TrEMBL E7BLD0
UniProt Splice Variant
Entrez Gene 281191
UniGene
RefSeq NP_847895
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF242855 GQ468554
GenPept AAF89171 ADM83590

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca