Version 5.4
Bos taurus Protein: PPP1R7
Summary
InnateDB Protein IDBP-695018.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R7
Protein Name Protein phosphatase 1 regulatory subunit 7
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000001045
InnateDB Gene IDBG-642551 (PPP1R7)
Protein Structure
UniProt Annotation
Function Regulatory subunit of protein phosphatase 1. Inactivates the PPP1CC isoform 2 during epididymal sperm maturation. {ECO:0000269PubMed:12444072, ECO:0000269PubMed:12826576}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in epididymal spermatozoa including the principal piece of the flagellum and the head-neck junction. {ECO:0000269PubMed:12444072}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0035307 positive regulation of protein dephosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003603 U2A\'/phosphoprotein 32 family A, C-terminal
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
SM00446
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3T0W4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 505297
UniGene Bt.48815
RefSeq NP_001029410
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102228
GenPept AAI02229

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca