InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PAICS

Summary

InnateDB Protein

IDBP-695034.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAICS

Protein Name

multifunctional protein ADE2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000013985

InnateDB Gene

IDBG-642524 (PAICS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.

Predicted by orthology
Total	43 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0004638	phosphoribosylaminoimidazole carboxylase activity
GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016829	lyase activity
GO:0042802	identical protein binding

Biological Process

GO:0006164	purine nucleotide biosynthetic process
GO:0006189	'de novo' IMP biosynthetic process

Cellular Component

GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain
IPR028923 SAICAR synthetase/ADE2, N-terminal

PFAM

PF00731
PF01259

PRINTS

PIRSF

SMART

SM01001

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q6PWM3

UniProt Splice Variant

Entrez Gene

404170

UniGene

Bt.64565

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AY573608 DAAA02017740

GenPept

AAS86200