InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CARD14

Summary

InnateDB Protein

IDBP-695160.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CARD14

Protein Name

caspase recruitment domain family, member 14

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020297

InnateDB Gene

IDBG-642674 (CARD14)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0050700	CARD domain binding

Biological Process

GO:0001934	positive regulation of protein phosphorylation
GO:0033209	tumor necrosis factor-mediated signaling pathway
GO:0042981	regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0051092	positive regulation of NF-kappaB transcription factor activity

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001315 CARD domain
IPR001452 SH3 domain
IPR001478 PDZ domain
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00619
PF00018
PF14604
PF00595
PF13180
PF00625

PRINTS

PR00452

PIRSF

SMART

SM00114
SM00326
SM00228
SM00072

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt