Version 5.4
Bos taurus Protein: CBX8
Summary
InnateDB Protein IDBP-695210.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CBX8
Protein Name chromobox protein homolog 8
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000012004
InnateDB Gene IDBG-642718 (CBX8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 81 interaction(s) predicted by orthology.
Predicted by orthology
Total 81 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003727 single-stranded RNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0035064 methylated histone binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0016574 histone ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0000790 nuclear chromatin
GO:0000792 heterochromatin
GO:0005634 nucleus
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
Protein Structure and Domains
PDB ID
InterPro IPR000953 Chromo domain/shadow
IPR016197 Chromo domain-like
IPR023780 Chromo domain
PFAM PF00385
PRINTS
PIRSF
SMART SM00298
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MBE9
UniProt Splice Variant
Entrez Gene 506458
UniGene Bt.12630
RefSeq NP_001071330
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049460
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca