Version 5.4
Bos taurus Protein: JPH2
Summary
InnateDB Protein IDBP-695266.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol JPH2
Protein Name junctophilin 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000053456
InnateDB Gene IDBG-642772 (JPH2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001786 phosphatidylserine binding
GO:0005515 protein binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0015278 calcium-release channel activity
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0070300 phosphatidic acid binding
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
Biological Process
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0055024 regulation of cardiac muscle tissue development
GO:0055074 calcium ion homeostasis
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016529 sarcoplasmic reticulum
GO:0030018 Z disc
GO:0030314 junctional membrane complex
Protein Structure and Domains
PDB ID
InterPro IPR003409 MORN motif
IPR017191 Junctophilin
PFAM PF02493
PRINTS
PIRSF PIRSF037387
SMART SM00698
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MNA0
UniProt Splice Variant
Entrez Gene 614651
UniGene
RefSeq XP_002692371
HUGO HGNC:14202
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02036707 DAAA02036708 DAAA02036709 DAAA02036710
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca