Version 5.4
Bos taurus Protein: MRI1
Summary
InnateDB Protein IDBP-695290.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRI1
Protein Name Methylthioribose-1-phosphate isomerase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003273
InnateDB Gene IDBG-642792 (MRI1)
Protein Structure
UniProt Annotation
Function Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). {ECO:0000255HAMAP-Rule:MF_03119}.
Subcellular Localization Cytoplasm {ECO:0000255HAMAP-Rule:MF_03119}. Nucleus {ECO:0000255HAMAP-Rule:MF_03119}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016853 isomerase activity
GO:0042802 identical protein binding
GO:0046523 S-methyl-5-thioribose-1-phosphate isomerase activity
Biological Process
GO:0008652 cellular amino acid biosynthetic process
GO:0009086 methionine biosynthetic process
GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine
GO:0019509 L-methionine biosynthetic process from methylthioadenosine
GO:0044237 cellular metabolic process
GO:0044249 cellular biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000649 Initiation factor 2B-related
IPR005251 Methylthioribose-1-phosphate isomerase
IPR011559 Initiation factor 2B alpha/beta/delta
PFAM PF01008
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2NL31
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 534734
UniGene Bt.10874
RefSeq NP_001039852
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111154
GenPept AAI11155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca