InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PGS1

Summary

InnateDB Protein

IDBP-695411.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PGS1

Protein Name

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000897

InnateDB Gene

IDBG-642907 (PGS1)

Protein Structure

UniProt Annotation

Function

Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003824	catalytic activity
GO:0005524	ATP binding
GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
GO:0016740	transferase activity
GO:0016780	phosphotransferase activity, for other substituted phosphate groups

Biological Process

GO:0006629	lipid metabolic process
GO:0006655	phosphatidylglycerol biosynthetic process
GO:0008152	metabolic process
GO:0008654	phospholipid biosynthetic process

Cellular Component

GO:0005739	mitochondrion
GO:0005783	endoplasmic reticulum

Protein Structure and Domains

PDB ID

InterPro

IPR001736 Phospholipase D/Transphosphatidylase
IPR016270 Phospholipase D, phosphatidylserine synthase type

PFAM

PF00614

PRINTS

PIRSF

PIRSF000850

SMART

SM00155

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2KJ28

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

535126

UniGene

Bt.12133

RefSeq

NP_001039860

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC105551

GenPept